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Did you mean agar and prostate (688 results)?
Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis.
Beyer U, Brand F, Martens H, Weder J, Christians A, Elyan N, Hentschel B, Westphal M, Schackert G, Pietsch T, Hong B, Krauss JK, Samii A, Raab P, Das A, Dumitru CA, Sandalcioglu IE, Hakenberg OW, Erbersdobler A, Lehmann U, Reifenberger G, Weller M, Reijns MAM, Preller M, Wiese B, Hartmann C, Weber RG. Beyer U, et al. Acta Neuropathol. 2017 Dec;134(6):905-922. doi: 10.1007/s00401-017-1774-y. Epub 2017 Oct 13. Acta Neuropathol. 2017. PMID: 29030706 Free article.
AGS is a genetically induced inflammatory disease particularly of the brain, which has not been associated with a consistently increased cancer risk to date. By targeted sequencing, we identified novel ADAR and RNASEH2B variants, and a 3- to 17-fold frequency increase of t …
AGS is a genetically induced inflammatory disease particularly of the brain, which has not been associated with a consistently increased can …
A concise review on the role of BDNF-AS in human disorders.
Ghafouri-Fard S, Khoshbakht T, Taheri M, Ghanbari M. Ghafouri-Fard S, et al. Biomed Pharmacother. 2021 Oct;142:112051. doi: 10.1016/j.biopha.2021.112051. Epub 2021 Aug 18. Biomed Pharmacother. 2021. PMID: 34426254 Free article. Review.
Notably, BDNF-AS has been reported to be down-regulated in colorectal cancer, osteosarcoma, esophageal cancer, glioblastoma, prostate cancer, cervical cancer and breast cancer. This lncRNA has direct/indirect functional interactions with GSK-3beta, EZH2, miR-214, PABPC1, R …
Notably, BDNF-AS has been reported to be down-regulated in colorectal cancer, osteosarcoma, esophageal cancer, glioblastoma, prostate …
A Comprehensive and Systematic Analysis Revealed the Role of ADAR1 in Pan-Cancer Prognosis and Immune Implications.
Zhu J, Zheng J, Zhang J, Wang S, Wang L, Zhao Y. Zhu J, et al. Dis Markers. 2023 Feb 21;2023:7620181. doi: 10.1155/2023/7620181. eCollection 2023. Dis Markers. 2023. PMID: 36865502 Free PMC article.
Moreover, ADAR1 expression was positively correlated with CD8(+) T cell infiltration levels in renal papillary cell carcinoma, prostate cancer, and endometrial cancer and negatively correlated with Treg cell infiltration. ...
Moreover, ADAR1 expression was positively correlated with CD8(+) T cell infiltration levels in renal papillary cell carcinoma, prostate …
Network neighborhood operates as a drug repositioning method for cancer treatment.
Cüvitoğlu A, Isik Z. Cüvitoğlu A, et al. PeerJ. 2023 Jul 10;11:e15624. doi: 10.7717/peerj.15624. eCollection 2023. PeerJ. 2023. PMID: 37456868 Free PMC article.
The similarity of these two networks was calculated by different network neighborhood metrics, including Adamic-Adar, PageRank and neighborhood scoring. The proposed approach identifies the best candidates by choosing the drugs with significant similarity scores. The metho …
The similarity of these two networks was calculated by different network neighborhood metrics, including Adamic-Adar, PageRank and ne …
Genetic markers associated with early cancer-specific mortality following prostatectomy.
Liu W, Xie CC, Thomas CY, Kim ST, Lindberg J, Egevad L, Wang Z, Zhang Z, Sun J, Sun J, Koty PP, Kader AK, Cramer SD, Bova GS, Zheng SL, Grönberg H, Isaacs WB, Xu J. Liu W, et al. Cancer. 2013 Jul 1;119(13):2405-12. doi: 10.1002/cncr.27954. Epub 2013 Apr 22. Cancer. 2013. PMID: 23609948 Free PMC article.
BACKGROUND: This study sought to identify novel effectors and markers of localized but potentially life-threatening prostate cancer (PCa), by evaluating chromosomal copy number alterations (CNAs) in tumors from patients who underwent prostatectomy and correlating these wit …
BACKGROUND: This study sought to identify novel effectors and markers of localized but potentially life-threatening prostate cancer ( …
PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3.
Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W. Salameh A, et al. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8403-8. doi: 10.1073/pnas.1507882112. Epub 2015 Jun 15. Proc Natl Acad Sci U S A. 2015. PMID: 26080435 Free PMC article.
Prostate cancer antigen 3 (PCA3) is the most specific prostate cancer biomarker but its function remains unknown. ...We show that PCA3 controls PRUNE2 levels via a unique regulatory mechanism involving formation of a PRUNE2/PCA3 double-stranded RNA that undergoes ad …
Prostate cancer antigen 3 (PCA3) is the most specific prostate cancer biomarker but its function remains unknown. ...We show t …
Quantification of microRNA editing using two-tailed RT-qPCR for improved biomarker discovery.
Voss G, Edsjö A, Bjartell A, Ceder Y. Voss G, et al. RNA. 2021 Nov;27(11):1412-1424. doi: 10.1261/rna.078867.121. Epub 2021 Aug 25. RNA. 2021. PMID: 34433636 Free PMC article.
For example, A-to-I editing of microRNAs through adenosine deaminase acting on RNA (ADAR) enzymes can affect their expression levels and functional roles, but editing isoform-specific assays are not commercially available. ...The assays could readily detect different miR-3 …
For example, A-to-I editing of microRNAs through adenosine deaminase acting on RNA (ADAR) enzymes can affect their expression levels …
Altered adenosine-to-inosine RNA editing in human cancer.
Paz N, Levanon EY, Amariglio N, Heimberger AB, Ram Z, Constantini S, Barbash ZS, Adamsky K, Safran M, Hirschberg A, Krupsky M, Ben-Dov I, Cazacu S, Mikkelsen T, Brodie C, Eisenberg E, Rechavi G. Paz N, et al. Genome Res. 2007 Nov;17(11):1586-95. doi: 10.1101/gr.6493107. Epub 2007 Oct 1. Genome Res. 2007. PMID: 17908822 Free PMC article.
Employing a bioinformatic approach, we identified significant global hypoediting of Alu repetitive elements in brain, prostate, lung, kidney, and testis tumors. Experimental validation confirmed this finding, showing significantly reduced editing in Alu sequences within ME …
Employing a bioinformatic approach, we identified significant global hypoediting of Alu repetitive elements in brain, prostate, lung, …
An autonomous molecular computer for logical control of gene expression.
Benenson Y, Gil B, Ben-Dor U, Adar R, Shapiro E. Benenson Y, et al. Nature. 2004 May 27;429(6990):423-9. doi: 10.1038/nature02551. Epub 2004 Apr 28. Nature. 2004. PMID: 15116117
As a proof of principle we programmed the computer to identify and analyse mRNA of disease-related genes associated with models of small-cell lung cancer and prostate cancer, and to produce a single-stranded DNA molecule modelled after an anticancer drug....
As a proof of principle we programmed the computer to identify and analyse mRNA of disease-related genes associated with models of small-cel …
13 results